Transgenic Mice Convert Carbohydrates to Essential Fatty Acids

Transgenic Mice Convert Carbohydrates to Essential Fatty Acids

Transgenic mice (named "Omega mice") were engineered to carry both optimized fat-1 and fat-2 genes from the roundworm Caenorhabditis elegans and are capable of producing essential omega-6 and omega-3 fatty acids from saturated fats or carbohydrates. When maintained on a high-saturated fat diet lacking essential fatty acids or a high-carbohydrate, no-fat diet, the Omega mice exhibit high tissue ...

Reduction of Chemical and Biological Oxygen Demands from Oil Wastes via Oleaginous Fungi: An Attempt to Convert Food by Products to Essential Fatty Acids

Background: The production of waste pollutants has become a major problem for many food and oil industries. However, oil wastes can provide alternative substrates for industry, which could help to solve environmental pollution problems. Furthermore, oil wastes can be used as substrates to produce unsaturated fatty acids, which are important for health. Objectives: The production of fatty acids ...

Consequences of Essential Fatty Acids

Essential fatty acids (EFA) are nutrients that form an amazingly large array of bioactive mediators that act on a large family of selective receptors. Nearly every cell and tissue in the human body expresses at least one of these receptors, allowing EFA-based signaling to influence nearly every aspect of human physiology. In this way, the health consequences of specific gene-environment interac...

Metabolism of Essential Fatty Acids

The fat deficiency disease in the rat (I), dog (2), and chick (3) is characterized in part by sharply increased concentrations of one or more trienoic acids in the tissues, as indicated by alkali isomerization analyses. Indeed, the increase in conjugatable triene in the mitochondrial fatty acids may be the first noticeable symptom of the onset of fat deficiency (4). The major triene component o...

Essential fatty acids and inflammation.